Case 224

MS 224.qxp

Background: Exogenous gamma-hydroxybutyrate (GHB) increases slow-wave sleep and reduces daytime sleepiness and cataplexy in patients with primary narcolepsy. Objective: To examine nighttime sleep and daytime sleepiness in a 13year-old girl homozygous for succinic semialdehyde dehydrogenase (SSADH) deficiency, a rare recessive metabolic disorder that disrupts the normal degradation of 4-aminobut...

224 - 230 Rohela M.pmd

We report a case of Hymenolepis diminuta infection in a 2-year-old Malaysian child. This case was initially reported as ‘normal’ after the examination of proglottids shed from the anus of the child at a private laboratory on two occasions. The putative proglottids shed was then referred to the Parasite Southeast Asia Diagnostic (Para:SEAD) Laboratory, Department of Parasitology, Faculty of Medi...

Bez nazwy-224

220-224 LCE Apr05qk

Introduction The identification and quantification of hexavalent chromium in solid samples is an important factor in characterization studies. The speciation of elements is a developing feature of analytical methods; the evaluation of the environmental and biological impact of the Cr (VI) compounds on environmental matrices is fundamental because of their demonstrated toxicity and potential car...

Dmd046292 224..229

Angiotensin II receptor blockers (ARBs) are used to treat hypertension. Most ARBs are metabolized by CYP2C9. The aim of this study is to evaluate the possible association between sex, polymorphisms in the CYP2C8 and CYP2C9 genes, and the pharmacokinetics of losartan, valsartan, candesartan, and telmisartan. The study population comprised 246 healthy volunteers from seven single-dose clinical tr...